Clinical Trials

  • Kidney Transplant in Recipients and Donors with HIV: Long-Term Follow-up Study

    Principal Investigator:

    Marcus Rebello Pereira, MD
    In this research study, we want to find out how well patients that receive a kidney from an HIV-positive (HIV+) donor do over 10 years compared to patients who receive a kidney from an HIV-negative (HIV-) donor. This research study is for adults who are HIV+ and are being evaluated for or are waitlisted to receive a kidney transplant. It is also available for adults who are HIV+ and previously received a kidney-only transplant under a HOPE Act protocol. To take part in this study you must be willing to accept a kidney from an HIV+ or HIV- donor. If you decide not to join this study, you will...

  • Liver Transplant from Donors with HIV for Recipients with HIV: Long Term Follow-up Study (HOPE)

    Principal Investigator:

    Marcus Rebello Pereira, MD
    The primary objective is to evaluate long-term outcomes in transplant recipients with HIV who receive livers from donors with HIV compared to donors without HIV. If you have any questions regarding this study, please contact the Transplant Clinical Research Center (TCRC).

  • Liver Transplant from Donors with HIV for Recipients with HIV: Long Term Follow-up Study (HOPE)

    Principal Investigator:

    Marcus Rebello Pereira, MD
    The primary objective is to evaluate long-term outcomes in transplant recipients with HIV who receive livers from donors with HIV compared to donors without HIV. If you have any questions regarding this study, please contact the Transplant Clinical Research Center (TCRC).

  • Screening for COVID-19 Vaccine, Prevention and Treatment Research Studies

    Principal Investigator:

    Magdalena E Sobieszczyk, MD, MPH
    We are looking for individuals over 18 years old who are interested in learning more about COVID-19 prevention research studies. We will ask you to complete a brief questionnaire to find out if you may be eligible for one of our studies. We can then schedule a phone call, teleconference, or in-person education visit so you can learn about the research we do and decide if you want to participate in one of our studies. Your responses to this questionnaire will be kept strictly confidential.

  • Stick2PrEP: Women/Trans/Non-Binary Individuals

    Principal Investigator:

    Magdalena E Sobieszczyk, MD, MPH
    Do you identify as a woman or transgender person, or do you have a non-binary gender identity? Has a medical provider ever diagnosed you with a sexually transmitted infection or recommended PrEP/another HIV prevention method? We are conducting a study to understand attitudes and preferences regarding HIV prevention methods among people who do not have HIV. The study involves taking online surveys. Some surveys are compensated. Please reach out if you are interested in hearing more about the study.

  • Study of Learning Mindfulness Meditation to Improve Symptoms in Patients with Long COVID

    Principal Investigator:

    Deborah A Theodore, MD
    This is a study for people with symptoms of long COVID. We are looking for people over the age of 18 who are interested in participating in a study to understand whether a mindfulness meditation intervention can help improve symptoms of long COVID. Study participation lasts 6 months and is fully remote.

  • Study of the COVID-19 Epidemic through Sewage for Columbia University Students and Employees

    Principal Investigator:

    Anne-Catrin Uhlemann, MD, PhD
    We want to examine if wastewater-based surveillance of SARS-CoV-2 is a valuable tool to detect SARS-CoV-2-positive individuals on campus prior to being identified by routine individual testing. We aim to enroll CU employees and students for active surveillance of SARS-CoV-2 carriage to be able to validate waste water surveillance findings. If successful this approach might inform targeted testing and can improve safety on campus.

  • Study of Vesatolimod (VES), GS-5423, and GS-2872 in PWH (People with HIV)

    Principal Investigator:

    Magdalena E Sobieszczyk, MD, MPH
    The purpose of this study is to look at whether these study drugs improve the bodys response to human immunodeficiency virus (HIV) in people with HIV (PWH) who started antiretroviral therapy (ART) early after getting HIV-1. The study treatments we are investigating are a study treatment vaccine, a study drug called vesatolimod (VES), and two broadly neutralizing antibodies (bNAbs; antibodies are natural proteins that the body makes in response to an infection), called GS-5423 and GS-2872. None of these experimental products has been approved by the US FDA except to be used in this research...

  • Transmission of COVID-19 in Households

    Principal Investigator:

    Delivette Castor, PhD
    We want to learn more about how COVID-19 virus is spread in the community and in the households. To answer this question, we are looking for people who test positive for COVID to measure how many of their close contacts also test positive, and how long the virus persists in the household. We will also study risk factors for getting COVID-19.

  • Treatment for Long-COVID: RECOVER-AUTO

    Principal Investigator:

    Lawrence James Purpura, MD, MPH, TM
    Certain investigational drugs (IVIG and Ivabradine) can help treat the system that controls automatic body functions such as heartbeat, blood pressure, and digestion associated with Long COVID. Long COVID is defined as symptoms associated with COVID that have lasted for at least 3 months and occur or worsen at least 1 month after infection. The study will enroll participants 18 years and older, with Long COVID, who experience Postural Orthostatic Tachycardia Syndrome (POTS), which is due to autonomic nervous system dysfunction. POTS is a condition that causes a number of symptoms when you...

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